Cincinnati vs. Indiana Odds Series: 2022 College Football Picks Week 4 Predictions from Proven Computer Model

The Indiana Hoosiers will be on the road for the first time this season when they take on the Cincinnati Bearcats on Saturday afternoon. They’ve won three straight at home to open the year, rallying from a 30-22 deficit in a 33-30 overtime victory over Western Kentucky last week. Cincinnati has rebounded from a narrow loss at then No. 19 Arkansas with wins over Kennesaw State and Miami (OH).

Kickoff is set for 3:30 p.m. ET. The Bearcats are favored by 16.5 points in the latest Cincinnati vs. Indiana from Caesars Sportsbook, while the over/under is set at 57. Before making any Indiana vs. Cincinnati picks, you’ll want to check out the college football predictions from the model at SportsLine.

The SportsLine projection model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a staggering profit of more than $3,300 for $100 players on college football’s top picks against the spread. He enters Week 4 of the 2022 college football season with a 51-43 streak across all the top college football picks and money lines dating back to 2021. Anyone who has followed has seen huge odds.

Now, the model has set its sights on Cincinnati vs. Indiana. You can head over to SportsLine to see his picks. Here are several college football odds for Indiana vs. Cincinnati:

  • Cincinnati vs. Indiana spread: Cincinnati -16.5
  • Cincinnati vs. Indiana over/under: 57 points
  • Cincinnati vs. Indiana picks: See picks here

Selected game | Cincinnati Bearcats vs. Indiana Hoosiers

Because Cincinnati can cover

This will be Indiana’s toughest opponent yet, and it’s also the first road game of the season, making this a tough scheduling spot. The Hoosiers are coming off an overtime thriller against Western Kentucky, adding another layer of difficulty to their preparation for this game. They have failed to cover the spread in two of their three wins this season and have covered just once in their last seven games overall.

Cincinnati may not have a perfect record, but they’ve looked like a good team again so far this season. The Bearcats narrowly missed covering the 6.5-point spread in a 31-24 loss at No. 19 Arkansas in Week 1, followed by blowout wins over Kennesaw State and Miami (OH). They are riding a 20-game home winning streak and have covered the spread in four of their last five games as favorites.

Because Indiana can cover

Indiana has been as resilient as any team in college football so far this season, using three comebacks to secure its three wins. The Hoosiers will be confident and motivated entering a matchup against a 2021 playoff team on Saturday afternoon. Quarterback Connor Bazelak completed 34 of 55 passes for 364 yards last week in a comeback win over Western Kentucky.

Cincinnati hasn’t been tested since Week 1, so it may take longer for the Bearcats to get into a competitive groove on Saturday. They have historically struggled against Big Ten teams, going 4-12 in their last 16 attempts. Indiana leads the all-time series 9-4-2 and was in position to win last season before three shutouts allowed Cincinnati to erase a 14-point deficit.

How to make Indiana vs. Cincinnati picks

The model has simulated Cincinnati vs. Indiana 10,000 times and the results are in. The model leans down, and has also produced a point spread option that reaches over 50% of the simulations. You can only see the selection on SportsLine.

So who wins Indiana vs. Cincinnati? And which side of the spread does more than 50% of the simulations hit? Visit SportsLine now to find out which side of the Cincinnati vs. Indiana contest to jump on Saturday, all from the model who has broken down his college football picks and find out.

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